Fandom: Mass Effect
Characters/Pairing/Other Subject: Shepard, the universe
Content Notes/Warnings: None
Medium: Digital art
Artist Website/Gallery: stellarstatelogic at deviantArt
Why this piece is awesome: This is part of an amazing series of artworks depicting the different endings in different art styles. They're all great but this is my favourite: a highly stylised art deco celebration of the fusion between organic and synthetic life that occurs in the "Control" ending.
Link: The Reaper War (Quarian Artstyle - Control Ending)

Fandom: Mass Effect
Characters/Pairing/Other Subject: Thane Krios/female Shepard
Content Notes/Warnings: None
Medium: Digitally coloured inked comic
Artist Website/Gallery: aimo on deviantArt
Why this piece is awesome: Mass Effect 3 is all about loss and finding hope in the face of despair. This is a lovely rendition of Thane and Shepard meeting again after the end.
Link: Across The Sea

Fandom: Mass Effect
Characters/Pairing/Other Subject: Tali
Content Notes/Warnings: None
Medium: Digital drawing
Artist Website/Gallery: makanidotdot
Why this piece is awesome: A much more interesting take on what Tali looks like under her mask than we got in canon. Totally adorable and alien and creepy and still hot :D
Link: Tali

As a result of I creating the link to makanidotdot's tumblr for this post I realised she has created ALL MY FAVOURITE TUMBLR MASS EFFECT FANART EVER. I managed to limit myself to only adding one more of her pictures to my queue of recs but you should definitely check her out :)